The PhoBR two-component system regulates antibiotic biosynthesis in Serratia in response to phosphate
Abstract Background Secondary metabolism in Serratia sp.ATCC 39006 (Serratia 39006) is controlled via a complex network of regulators, including a LuxIR-type (SmaIR) quorum sensing (QS) system.Here we investigate the molecular mechanism by which phosphate limitation controls biosynthesis of two antibiotic secondary metabolites, prodigiosin and carb